منابع مشابه
The Role of Atoh1 in Mucous Cell Metaplasia
A key issue in otitis media is mucous cell metaplasia which is responsible for mucous hypersecretion and persistence of the disease. However, little is known about the molecular mechanisms of mucous cell metaplasia in otitis media. Numerous studies of intestinal epithelial homeostasis have shown that Atonal homolog 1 (Atoh1), a basic helix-loop-helix (bHLH) transcription factor, is essential fo...
متن کاملMucin Production and Mucous Cell Metaplasia in Otitis Media
Otitis media (OM) with mucoid effusion, characterized by mucous cell metaplasia/hyperplasia in the middle ear cleft and thick fluid accumulation in the middle ear cavity, is a subtype of OM which frequently leads to chronic OM in young children. Multiple factors are involved in the developmental process of OM with mucoid effusion, especially disorders of mucin production resulting from middle e...
متن کاملMucous metaplasia of the pleura.
A case of mucous metaplasia of mesothelium in an 80 year old woman is described. Its cause is unknown, but it is important not to confuse it with secondary tumour.
متن کاملImmunogenetic programs for viral induction of mucous cell metaplasia.
Mucous secretions are frequently implicated in the morbidity and mortality associated with respiratory illness and airway disease, but we still do not understand precisely how these secretions develop or how to control them. A likely possibility is that the increased mucus is a consequence of overproduction and subsequent secretion in the setting of mucous cell metaplasia. In that regard, airwa...
متن کاملFluticasone propionate attenuates ozone-induced rhinitis and mucous cell metaplasia in rat nasal airway epithelium.
Ozone (O3) is the principal oxidant pollutant in photochemical smog. Repeated exposures to O3 induces inflammation and mucous cell metaplasia in the nasal airways of laboratory animals. Our study was designed to determine the efficacy of a topical anti-inflammatory corticosteroid in preventing O3-induced rhinitis and mucous cell metaplasia in rat nasal epithelium. Male F344 rats were exposed to...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2010
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2009-0151tr